ProBE Lab

Ph.D. Students

Rohini Shankar

I’m a graduate student working towards a Ph.D in Biomedical Engineering. I’m originally from India and have a double masters in Electrical Engineering and Physics. My previous research mainly focused on image reconstruction techniques in medical imaging, particularly in computed tomographic (CT) imaging. My research at Monash University, Australia, was in the area of tissue specific CT wherein I employed synchrotron radiation based techniques to image hard and soft atherosclerotic plaques in mouse hearts ex vivo. I plan to pursue postdoctoral studies on completing my Ph.D and would like to pursue a research career in an academic setting. My current research with Dr. Kodibagkar involves applying the technique of compressed sensing to magnetic resonance spectroscopic imaging (MRSI), to reduce the acquisition time of spectroscopic data. The objective is to exploit the inherent sparsity in MR images and perform prospective under sampling in the k-space to reduce the total scan time in conventional MRSI.

 

 

Shubhangi Agarwal

ShubhangiI am pursuing my Ph.D. in Biomedical Engineering and have been a part of Probe lab since August 2012. I completed my Bachelors in Biotechnology from India and Masters in Biomedical Engineering from University Of Texas at Dallas where I worked in Macromolecular Structure & Engineering Research Lab and my project was crystallization of P. physarum mitochondrial RNA Polymerase Protein  ( E.Coli Derived Protein). In Probe lab I started with working on formation of Siloxane based Nano-emulsions and moved on to development of Dual Modality Nanoprobes applicable for both MRI and Flourescence imaging. I then started working on tumor oxygenation imaging using the two novel MRI oximetry techniques unique to our lab. My research is focused on assessment of changes in oxygenation of pre-clinical models of human cancer as a response to hypoxia activated therapeutics. Hypoxia is an important hallmark of cancer and presents itself as a marker for tumor diagnosis and development of cancer therapeutics. The primary goal of my research is to test the hypothesis that prospective identification of hypoxic tumors is important in successful treatment of tumors and also for the development of better therapeutic protocols. The long term goal of my proposed research is the clinical translation of both the MRI techniques and their use in determining the pattern of tumor hypoxia pertaining to an individual patient tumor.

 

Vimala Bharadwaj

I am currently a Ph.D. student in Biomedical Engineering. I completed my B.S. in biotechnology from Dayanada Sagar College of Engineering (KA, India) in 2011. Due to my passion for engineering application in human health care, I pursued my masters in Biomedical Engineering from Arizona State University (AZ, U.S.A) and completed in 2013. As part of my M.S. degrees, I worked on investigating the inflammatory response (astrocytes and macrophages) due to brain injury and realized my interest for engineering application in neuroscience. Taking it further, my PhD research focuses on investigating the optimal delivery of nanoparticles after traumatic brain injury (based on their size and injection time), and results indicate the accumulation of up to 500 nm nanoparticles after acute brain injury. The potential applications of this project are exciting and far-reaching, including nanoparticles-based strategies to develop precise prognosis and efficient theranostic after acute brain injury. I am co-mentored by Dr. Kodibagkar, and Dr. Stabenfeldt, who are also my role models! After completing my PhD, I plan to pursue post-doctoral research revolving around my passion for application in neuroscience and hope to establish a career in academia. Outside of my research world, I love music and running, and my favorite actor of all time is Amitabh Bachchan.

 

Nutandev Bikkamane Jayadev

IMG_ASUI am a graduate student, pursuing my Ph. D in Biomedical Engineering. I have a Masters degree in Biomedical Signal Processing and Instrumentation from Dayanada Sagar College of Engineering (KA, India).  My master’s thesis work was focused on developing a novel method in acquiring k-space data in MRI which involved the design of arbitrary k-space trajectories and their respective optimal gradient waveforms. In future, I will pursue postdoctoral studies and continue as a research engineer.  My current research with Dr. Vikram Kodibagkar involves application of compressed sensing to magnetic resonance spectroscopic imaging (MRSI).