ProBE Lab



Post Docs

DuongDuong T Nguyen

Duong completed her undergraduate study at Texas Woman’s University with a major in Chemistry and a minor in Mathematics. After receiving her Ph.D. in Chemistry from University of North Texas, she joined the laboritories of Stabenfeldt and Kodibagkar to study magnetic resonance imaging (MRI) contrast agent for traumatic brain injury. Her project was focused on developing multifunctional iron oxide nanoparticles.





Christopher Rock

Postdoctoral research fellow from 2018-2019 whose research dealt with the design and synthesis of hypoxia sensitive MRI contrast agents and the development of polymethacrylate pH sensitive imaging probes. Joint research was conducted between ASU School of Biological and Health Systems Engineering and ASU School of Molecular Sciences.

B.S. Through Ph.D.         

Carlos RenteriaCarlos Renteria

B.S.E. Biomedical Engineering, Arizona State University, 2016

Past Research: Involved in the co-registration of hypoxia-enhanced MR images with pimonidazole-stained images to test the efficacy of a novel hypoxia-binding contrast agent, GdDO3NI. We hope to use this agent as a tool for imaging hypoxia in-vivo for use as a diagnostic and prognostic tool. This would allow for more efficient, non-invasive diagnosis of cancer, as well as potential for tracking the effectiveness of various cancer treatments over time by tracking tumor-hypoxia.

Luke_pictureLuke Lammers

B.S.E. Biomedical Engineering, Arizona State Univeristy, 2016

Past Research: His honors thesis project was centered around creating a graphical user interface (GUI) for compressed sensing magnetic resonance spectroscopy (MRSI). The GUI aimed to be able to integrate various scanner types into a single computing platform that can perform both clinical and preclinical analysis. He hopes that this project will improve how researchers and clinicians use compressed sensing MRSI in the future.

CourtneyDuBoisCourtney Dubois

B.S.E. Biomedical Engineering, Arizona State University, xxx

Past Research: To incorporate a carbohydrate glass structure within a multicellular spheroid in order to simulate tumor vasculature for in vitro cells and study tumor hypoxia. Tumor hypoxia creates a demanding microenvironment and it is a contributing factor to tumor aggression, often resulting in an increase of metastasis, chemoresistance, radioresistance, and even anticancer drug resistance. Thus it is important to study tumor hypoxia, as it can provide information on the type of treatment regime most effective for killing cancer cells.

Tobey, JohnJohn Tobey

B.S.E. Biomedical Engineering, Arizona State University, 2017 M.S. Biomedical Engineering, Arizona State University, 2018

Past Research: Research involved the creation of radio frequency probes for imaging mesoscale tumor spheroids, and the evaluation of the efficacy of GdDO3NI, a gadolinium-based hypoxia marker, for studying the distribution of hypoxia in multicellular tumor spheroids. The ultimate purpose of this was to find the best incubation protocol such that high resolution images of the 3D spatial variations of hypoxia can be obtained and analyzed.


profRichard Li

B.S.E. Biomedical Engineering, Arizona State University, xxx

Past Research: Research was centered around nanoprobes that were designed to report oxygenation levels in tumor tissue. These nanoparticles are siloxane based and loaded with pimonidazole, a novel hypoxia marker. The ability to report oxygenation levels in a tumor is critical to therapy in that tumors that are hypoxic (lack oxygen) are significantly harder to treat. Therapies can be tailored with this knowledge in mind and allow for much more effective treatment.


Krishnakanth Chitta

M.S. Biomedical Engineering, Arizona State University, xxx                                                                                                      B.S.E. Biomedical Engineering, Arizona State University, xxx 

Past Research: My research focus was on utilizing Multi Parametric Magnetic Resonance Imaging for characterizing physiologic microenvironment of brain tumors and  performing quantitative studies to evaluate of clinical efficacy of Azacytidine drug and DC vaccine. My work involved employing image segmentation algorithms and evaluating quantitative information using Diffusion Tensor Imaging methods.

Rohini Shankar                                                                                                                       

Ph.D. Biomedical Engineering, Arizona State University, xxx                                                                                                              M.S. Electrical Engineering, xxx, xxx                                                                                                                                                      M.S. Physics, xxx, xxx                                                                                                                                                                                B.S. Bioengineering, xxx, xxx


Past Research: Applied the technique of compressed sensing to magnetic resonance spectroscopic imaging (MRSI), to reduce the acquisition time of spectroscopic data. The objective was to exploit the inherent sparsity in MR images and perform prospective under sampling in the k-space to reduce the total scan time in conventional MRSI.



ShubhangiShubhangi Agarwal                                                                             

Ph.D. Biomedical Engineering, Arizona State University, 2017                                                                                                                      M.S. Biomedical Engineering, University of Texas at Dallas, 2012                                                                                                            B.S. Biotechnology, Amity University Delhi, 2010


Past Research: Started work on the formation of siloxane based nanoemulsions and moved onto the development of Dual Modality Nanoprobes applicable for both MRI and Fluorescence imaging. Worked in tumor oxygenation imaging using the two novel MRI oximetry techniques unique to our lab. My research was focused on assessment of changes in oxygenation of pre-clinical models of human cancer as a response to hypoxia activated therapeutics.


Vimala Bharadwaj                                                                               

Ph.D. Biomedical Engineering, Arizona State University, 2018                                                                                                M.S. Biomedical Engineering, Arizona State University, 2013                                                                                                  B.S. Biotechnology, Dayanada Sagar College of Engineering (KA, India), 2011

Past Research: Focused on investigating the optimal delivery of nanoparticles after traumatic brain injury (based on their size and injection time), and the results indicated the accumulation of up to 500 nm nanoparticles after acute brain injury. Applications revolve around nanoparticles-based strategies to develop precise prognosis and efficient theranostic after acute brain injury.         



website pictureAlex Cusic

M.S. Biomedical Engineering, Arizona State University, 2014                                                                                                                      B.S. Bioengineering, Clemson University, 2012


Past Research: Cell labeling for improved MRI contrast through fabrication of polydimethylsiloxane (PDMS) nanoemulsions, with a focus on neural stem cells.



BharatBharat Annalda

M.S. Biomedical Engineering, Arizona State University, 2014                                                                                                                      B.S.E. Biomedical Engineering, Mumbai University, 2010


Past Research: Obtaining prognostic information non-invasively using MRI techniques at early stages of traumatic brain injury and brain tumor. Development of image processing algorithms in MATLAB for quantitative analysis of MRI parametric maps  and fiber tracking using diffusion tensor imaging (DTI) technique.


Eugene Chung

B.S.E. Biomedical Engineering, Arizona State University, 2016

Past Research: Creating tumor spheroids in order to test hypoxia sensitive MRI contrast agents. Testing of dual modality siloxane based nanoemulsions loaded with Nile red, which work as both MRI and fluorescence probes for cancer therapeutics and diagnostics.

Martin_Jonathan_7381aJonathan Martin

B.S.E. Chemical Engineering and Computational Mathematical Sciences, Arizona State University, 2014


Past Research: Time-dependent DCE-MRI data to quantify the perfusive properties of tumorous tissue.




Grucky_Marian_7364aMarian Grucky

B.S. Biomedical Engineering, Arizona State University, 2013


Past Research: Characterizing cytotoxic effects of cyclophosphamide on prostate cancer cells at various doses and levels of tumor oxygenation.




Hussain_Hyder_7360aKhateeb Hyder Hussain

B.S.E. Biomedical Engineering, Arizona State University, 2014


Past Research: Generating nanoparticles for use as MR contrast agents.





Poling_Chelsey_7346aChelsey Poling

B.S.E. Biomedical Engineering, Arizona State University, 2013


Past Research: Focused on characterizing the OMDSO molecule and assessing its usefulness as a pO2 reporter molecule.




lakshmiLakshmi Kandagaddala

Ph.D. Biomolecular Science, Korea Institute of Science & Technology (KIST) (Seoul, South Korea), xxx                                            M.S. Biochemistry, Sri Krishnadevaraya University (Kurnool, India), xxx                                                                                                    B.S. Biochemistry, Sri Venkateswara University (Kadapa, India), xxx


Past Research: Research Tech in Dr. Kodibagkar’s lab. Focused on detecting the biomarkers for hypoxia in tumor sections by Immunofluorescence and preparation of nanoemulsions formulations.