US Department of Defense (DOD) ARMI BioFAB USA                                                   

5/1/2019-6/1/2021

Title: Adaptable Multi-Modality Nanoprobes for Non-Invasive Real-Time Monitoring of Engineered Cells and Tissues

Role: Co-Principal investigator

The major goal of this proposal is to develop biocompatible, multimodality pH and pO2 sensing nanoprobes for integration into neural stem cell transplants. 

National Institutes of Health (NIH) 1UF1NS107676-01                                                 

6/1/2018-5/31/2021     

Title: Quantitative mapping of oxygenation around neural interfaces using novel PISTOL MR imaging

Role: Co-Principal investigator

The major goal of this proposal is to develop a novel MR based imaging technology to map oxygen tension around microscale neural interfaces in the brain. 

Dignity Health-Arizona State University Seed Grant                                                    

9/24/2018-1/31/2021     

Title: One shot morphologic, hemodynamic and metabolic MR imaging of brain tumors.

Role: Principal investigator

The major goal of this proposal is to develop a novel 1H MR based imaging technique to map hypoxia and perfusion in brain tumors.

**Five research awards completed during the last three years are listed below**

National Science Foundation CAREER Award                                                             

05/15/14-05/14/19 

Title: Quantitative Imaging of Tissue Oxygenation                                                                                       

Role: Principal investigator

The goal of this study is to develop pharmacokinetic models for dynamic time course data from 1H MR methods of assessing tissue oxygenation developed by the PI using GdDO3NI and siloxanes.

Banner MD Anderson Cancer Center Research Contract                                              

08/08/14-12/31/18

Title: Evaluation of New Magnetic Resonance (MR) Imaging and Spectroscopy Software

Role: Principal investigator

The goal of this project is the clinical implementation and use of compressed sensing based fast MRSI for abdominal cancer patients.

Flinn Foundation Award                                                                                                        

11/01/14-5/31/17                                

Title: Next Generation Precision Diagnostics for Brain Injury

Role: Co-Principal investigator

The goal of this study is to develop targeted nanoparticle agents for traumatic brain injury.

National Institutes of Health (NIH) R01                                                                          

03/15/14–02/28/18

Title: Direct Functional Imaging of Electrical Brain Stimulation (PI: Sadleir)                                   

Role: Co-investigator

The goal of this study is to develop MR methods for functional imaging of electrical brain stimulation.

DARPA/BTO N66001-17-2-4018

04/20/17-04/19/20

Title: TENPO – transdermal neuromodulation (PI: Helms-Tillery)                                 

Role: Co-investigator

The major goal of this research is to understand mechanisms of transdermal neuromodulation in monkey models and human subjects.